Magnesium upregulates insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide-induced type-2 diabetic rats
نویسندگان
چکیده
منابع مشابه
The comparison of continuous and intermittent training impact on glucose-4 transporter protein level and insulin sensitivity in diabetic rats
Introduction: Diabetes mellitus (DM) is now seen as a worldwide epidemic disease with high prevalence. Exercise training (ET) is known to promote beneficial changes in diabetic patients. The aim of this study was to compare the impact of continuous and intermittent aerobic training on glucose-4 transporter protein (GLUT-4) levels and insulin sensitivity in diabetic rats. Materials and meth...
متن کاملHypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide/streptozotocin-induced type 2 diabetic rats
BACKGROUND The present investigation was aimed at evaluating the hypoglycemic and hypolipidemic properties of the aqueous and methanolic extracts from Bersama engleriana leaves in streptozotocin/nicotinamide (STZ-NA)-induced type 2 diabetic rats. METHODS Animals were orally treated for 4 consecutive weeks with Bersama engleriana extracts at doses of 300 or 600 mg/kg. The anti-diabetic effect ...
متن کاملEffect of silymarin on streptozotocin-nicotinamide-induced type 2 diabetic nephropathy in rats.
INTRODUCTION Diabetic nephropathy is the major cause of end-stage renal disease worldwide. Silymarin is a flavonoid mixture obtained from Silybum marianum. Various preclinical and clinical studies have revealed that it has antidiabetic activity. The objective of this study was to evaluate the effect of silymarin on type 2 diabetic nephropathy in rats. MATERIALS AND METHODS Non-insulin-depende...
متن کاملAntidiabetic and hypolipidemic effects of Dorema aucheri hydroalcoholic leave extract in streptozotocin-nicotinamide induced type 2 diabetes in male rats
Objective(s):The present study investigated the antidiabetic and hypolipidemic properties of Dorema aucheri leave hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats. Materials and Methods: nicotinamide/streptozotocin-induced diabetic rats were supplemented orally with three different doses of D. aucheri (100, 200 and 400 mg/kg BW) or glibenclamide (0.25 mg/kg) f...
متن کاملEffect of C-peptide Alone or in Combination with Nicotinamide on Glucose and Insulin Levels in Streptozotocin-Nicotinamide-Induced Type 2 Diabetic Mice.
BACKGROUND Both C-peptide and nicotinamide are known to reduce blood glucose in type 1 diabetes. In the present study, the effects of C-peptide alone or in combination with nicotinamide on glucose and insulin levels in streptozotocin-nicotinamide-induced type 2 diabetic mice. METHODS The study used 70 adult male NMARI mice, weighing 25-35 g, divided into seven groups: control; type 1 diabetic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine Regulations
سال: 2018
ISSN: 1336-0329
DOI: 10.2478/enr-2018-0002